Optogenetic fMRI: Genetically Targeted Brain Circuit Debugging

Jin Hyung Lee
University of California, Los Angeles

Thursday, July 29, 2010 at 3:00pm
Engr IV Maxwell Room 57-124

Abstract
Using a novel methodology integrating Optogenetics with high-field fMRI, we show highly specific in vivo circuit identification, in which the functional role of cell types defined by location, genetic identity, and topology can be directly observed and globally mapped in the living mammal.

Biography
Jin Hyung Lee is an Assistant Professor of Electrical Engineering, Bioengineering, Psychiatry and Biobehavioral Sciences, and Radiology at the University of California, Los Angeles (UCLA). Dr. Lee received her Bachelor's degree from Seoul National University ('98) and Masters ('00) and Doctoral degree ('04) from Stanford University, all in Electrical Engineering. She is a recipient of the NIH/NIBIB K99/R00 pathway to independence award and she is the pioneer of the optogenetic fMRI (ofMRI) technology (Nature, May 16 2010).